Human Hair Keratin Microspheres Prepared by the Water-In-Oil Emulsion Solvent Diffusion Method for Hydrophilic Drug Carrier
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چکیده
منابع مشابه
Novel preparation method for sustained-release PLGA microspheres using water-in-oil-in-hydrophilic-oil-in-water emulsion
An increasing number of drugs are needing improved formulations to optimize patient compliance because of their short half-lives in blood. Sustained-release formulations of drugs are often required for long-term efficacy, and microspheres are among the most popular ones. When drugs are encapsulated into microsphere formulations, different methods of preparation need to be used according to spec...
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The objective of the current investigation is to reduce dosing frequency and improve patient compliance by designing and systematically evaluating sustained release microspheres of Glipizide. An anti-diabetic drug, Glipizide, is delivered through the microparticulate system using ethyl cellulose as the controlled release polymer. Microspheres were developed by the emulsion solvent diffusion-eva...
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The aim of this study was to evaluate microencapsulated controlled release preparations of tolmetin sodium using ethylcellulose as a retardant material. Microspheres were prepared by using water-in-oil-in-oil (W/O(1)/O(2)) double-emulsion solvent diffusion method, using different ratios of ethylcellulose to tolmetin sodium. Span 80 was used as the droplet stabilizer and n-hexane was added to ha...
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80% except for acetaminophen, due to its lower solubility in water and higher solubility in corn oil. The release profile of the drug was pH dependent. In acidic medium, the release rate was much slower, however, the drug was released quickly at pH 7.4. Tacrine showed unexpected release profiles, probably due to ionic interaction with polymer matrix and the shell structure and the highest relea...
متن کاملBiodegradable Poly(D,L-lactide)/Lipid Blend Microparticles Prepared by Oil-in-Water Emulsion Method for Controlled Release Drug Delivery
The effects of blend ratio and drug loading content of poly(D,L-lactide) (PDLL)/stearic acid blends on microparticle characteristics and drug release behaviors were evaluated. The blend microparticles were prepared by an oil-in-water emulsion solvent evaporation method for drug delivery of a poorly water-soluble model drug, indomethacin. The microparticles were characterized using a combination...
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ژورنال
عنوان ژورنال: Oriental Journal of Chemistry
سال: 2019
ISSN: 0970-020X,2231-5039
DOI: 10.13005/ojc/350326